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96,97 Moreover, the ME1 protein is hypophosphorylated at S336 and hyperacetylated at K337 by PGAM family member 5 and acetyl-CoA acetyltransferase, respectively, resulting in ME1 translocation from mitochondria to the cytosol, dimerization and activation, thus strongly promoting NADPH generation and tumorigenesis

These changes include higher levels of Enterococcus and Streptococcus species and increased Enterobacteriaceae , while beneficial Bifidobacteria and anti-inflammatory Firmicutes are decreased [21,22,23, 27]

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From the study reviewed, it showed that UQ reduces oxidative stress and did not lead to any adverse effects

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